St. Anna Children's Hospital


The St. Anna children's hospital evolved from the once first Austrian children's hospital to an institution providing state-of-the-art medical care. Under the leadership of Prof. Helmut Gadner who acted as Medical Director of the St. Anna children's hospital (1981 - 2011) the hospital continuously developed since 1981 from being a provider of services as a general children's hospital to a treatment centre for paediatric blood and tumour diseases (cancer) and therefore has an excellent reputation both throughout Austria and internationally. As of March 2012 Univ. Prof. Wolfgang Holter is acting as Medical Director.

The hospital has a total of eight wards including a baby unit, two general-paediatric wards, an ENT ward, two oncologic base wards, a bone marrow transplantation ward and an in-house intensive care unit which is primarily used for the supervision of patients after bone marrow transplantations.

In addition to the general-paediatric area there is a general outpatient department (including a 24/7 emergency outpatient clinic) with further specialised outpatient departments for first care and aftercare. The outpatient departments for oncology, haematology, immunology and also stem cell transplantation and aftercare are located in the haematological-oncologic area. Since summer 1997 a day unit of the oncologic base wards is in operation. State-of-the-art facilities and equipment are available to accurately diagnose diseases.

St. Anna children's hospital takes on all treatments of internal paediatric diseases and all ENT surgeries. All other surgeries take place in collaboration with other hospitals. However, the responsibility of care before and after the procedure remains with St. Anna children's hospital.

Approximately 365 staff members (full-time equivalents) are available for patient care; these include 53 physicians, 167 nursing personnel and also medical-technical qualified personnel, physiotherapists, language therapists and dietologists.

The care and support of oncologic and internal areas by psychologist and psychotherapist also must be mentioned here. In addition social workers and church ministers also provide support. Nursery school teachers and "The Yellow Aunts" (voluntary staff) make sure patients are experiencing distraction and fun through games or creative activities. CliniClowns also visit the hospital on a regular basis. In case of long-term treatments our patients will be taught by teachers of the "Heilstättenschule" Vienna, a regular school for children staying in hospital for an extended period.

S²IRP - Studies and statistics at St. Anna children's cancer research (

Supported by affected parents, whose children had developed cancer and were treated at St. Anna children's hospital, a research institute for those children has been established there under the direction of Prof. Helmut Gadner in June 1988.

Within that institute a competence centre for studies and statistics with the emphasis on academic haemato-oncological studies was established. Due to the variety of tasks the institute was renamed S²IRP (Studies and Statistics for Integrated Research and Projects); based on an audit it was relocated in 2006 to Hebragasse 9 which is still close to St. Anna children's hospital but provides more space. Since 2004 St. Anna children's cancer research assumed the legally required sponsor-responsibility as per EU requirements and MPA for those academic studies and also secured continued existence by signing an insurance framework agreement for all of Austria with Zurich-Kosmos in September 2005.

Under the control of Univ. Prof. Dr. Ruth Ladenstein (paediatrician specialised in haemato-oncology, also qualified in project management and holder of an MBA degree, director of the task force for haemato-oncology AGPHO [task force meeting paediatric haemato-oncology] of the ÖGKJ [Austrian Society for Paediatric and Adolescent Medicine] academic therapy studies with the subject matter of the broad range of cancer are carried out in close co-operation with St. Anna children's hospital and a multidisciplinary team with the objective of the qualitative and quantitative improvement of survival. Taking into account relevant translational research results, new findings in the area of diagnostics and therapy for risk-adapted treatments are utilised.

To date the competence centre for studies and statistics has ascertained data of over 9.000 cancer patients; those data was analysed and communicated in the form of lectures and numerous publications both on national and international level. In terms of clinical pictures the international focus particularly is on Langerhans cell histiocytosis (controllership of LCH studies I-IV), neuroblastoma (controllership of the European high-risk neuroblastoma study HR-NBL1/SIOPEN) and on stem cell transplantation in case of acute lymphatic leukaemia (controllership of the international ALL-SCT study).

S²IRP provides competence and the full range of support with regard to planning, organisation and execution of clinical studies in accordance with legal requirements to both researchers and partners in the industry. The services include consulting, production of necessary documents (study protocols, patient information, case report forms), support in data base development, the carrying through of ethical committees' and public administrations' approvals and also fulfilment of various documentation and reporting obligations, handling of trial medication, planning and monitoring of pharmacovigilance management and project management. All Austrian haemato-oncologists of the AGPHO were trained to be principal investigators and the team of research and study assistants are also trained through numerous medical education courses.


Zimmermannplatz 10
A-1090 Wien
Tel.: +43 (0)1 40470 0
Fax: +43 (0)1 40470 7150

Univ. Prof. Dr. Ruth Ladenstein, MBA, cPM